Prenol lipids
Medchemexpress LLC β-Amyrin acetate | 1616-93-9 | 5 MG
This product is a triterpenoid with various biological activities, including anti-inflammatory, antifungal, anti-diabetic, and anti-hyperlipidemic effects. It functions by inhibiting the activity of an enzyme called HMG-CoA reductase.
- Potent anti-inflammatory activity.
- Antifungal properties.
- Anti-diabetic effects.
- Anti-hyperlipidemic activity.
- Inhibits HMG-CoA reductase.
Sigma Aldrich Fine Chemicals Biosciences (±)-α-Tocopherol | 10191-41-0 | MFCD00072051 | 50g
(±)-α-Tocopherol | MW:430.71 | 10191-41-0 | MFCD00072051 | 50g
Medchemexpress LLC PNC-28 acetate | 392661-17-5 | 98.8% | 3509.13 | 5 MG
PNC-28 acetate is a peptide derived from the p53 protein, identified as an anticancer agent. It is used in pancreatic cancer research.
- Derived from the mdm-2-binding domain (residues 17-26) of the p53 protein
- Contains a membrane crossing-penetratin sequence
- Blocks the growth of a lethal human pancreatic cancer cell line
- Inhibits BMRPA1.Tuc3 tumor growth in vivo
Apexbio Technology LLC Bazedoxifene acetate 198481-33-3 25mg
Bazedoxifene acetate (CAS 198481-33-3) is a selective estrogen receptor modulator (SERM) targeting estrogen receptors (ER) It is designed to modulate ER activity thereby regulating estrogen-dependent cellular pathways Bazedoxifene acetate exerts its biological activity primarily through tissue-specific agonism and antagonism of ER In in vitro studies Bazedoxifene acetate demonstrates receptor modulation with reported affinities (Ki) of 26 nM for ER and 99 nM for ER Based on these pharmacological properties Bazedoxifene acetate holds research potential in osteoporosis and bone metabolism studies as well as in investigations of hormone-responsive cellular mechanisms and pancreatic cancer
Medchemexpress LLC ATIC-IN-1 acetate | 3067165-96-9 | C23H37N7O7 | 5 MG
ATIC-IN-1 acetate is an inhibitor targeting Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization, with a Ki value of 685 nM. This compound catalyzes de novo purine biosynthesis, and ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. It exhibits anti-tumor activity by reducing cell numbers and cell division rates.
- Targets ATIC dimerization.
- Exhibits anti-tumor activity via reduction in cell numbers and cell division rates.
- Shows nonspecific aggregate mechanism in the presence of 1 mg/mL and 10 mg/mL BSA.
- Inhibits the proliferation of MCF-7 cells (100-500 μM; 48 h).
- Reduces cell division rather than increasing cell death (250 μM; 24-72 h).
Medchemexpress LLC Genipin ((+)-Genipin) | 6902-77-8 | 99.8% | 226.23 | 50 MG
Genipin is a natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. It inhibits UCP2 (uncoupling protein 2) in cells and exhibits various bioactivities. This product is suitable for research on protein modulation, antitumor, anti-inflammation, immunosuppression, antithrombosis, protection of hippocampal neurons, and type 2 diabetes.
- Inhibits UCP2 in cells
- Exhibits protein modulation, antitumor, anti-inflammation, immunosuppression, antithrombosis, and hippocampal neuron protection
- Useful for type 2 diabetes research
- Increases mitochondrial membrane potential and ATP levels
- Stimulates insulin secretion in pancreatic islet cells
- Activates pathways leading to glucose transporter 4 translocation and increased glucose uptake
- Increases cytochrome c content in the cytosol of treated FaO cells
- Activates caspase-3 and caspase-7, contributing to apoptotic processes
Selleck Chemical LLC a-Terpineol
-Terpineol a natural monoterpene is the major component of essential oils of several species of aromatic plants such as Origanium vulgare L and Ocimum canum Sims which are widely used for medicinal purposes It is widely used in the manufacturing of cosmetics soaps perfumes antiseptic agents and is considered one of the most frequently used fragrance compounds -TPN has anticholinergic action and can block the interaction between PGE2 and GM1 receptors and cholera toxin
Selleck Chemical LLC Ursonic acid S3902-25mg
Ursonic acid (Prunol Malol beta-Ursolic acid NSC4060 CCRIS 7123 TOS-BB-0966) present in many plants is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives such as experimental antitumor agents Ursonic acid induces the apoptosis of human cancer cells through multiple signaling pathways
Medchemexpress LLC Dihydrotanshinone I | 87205-99-0 | 278.30 | 100 MG
Dihydrotanshinone I is a natural compound extracted from *Salvia miltiorrhiza Bunge*, which has been widely used for treating cardiovascular diseases. It exhibits an entry-blocking effect for MERS-CoV.
- Natural compound extracted from *Salvia miltiorrhiza Bunge*.
- Used for treating cardiovascular diseases.
- Exhibits an entry-blocking effect for MERS-CoV.
Cayman Chemical BetulInIc Aldehyde oxIme 50mg
A derivative of betulin; active against E. aerogenes, E. coli, E. faecalis, P. aeruginosa, S. aureus, and C. albicans, as well as L. donovani amastigotes, at 50 µM; is cytotoxic to Huh7 hepatocellular carcinoma cells at 50 µM
Medchemexpress LLC 18α-Glycyrrhizic acid | 83896-44-0 | 50 MG
18α-Glycyrrhizic acid is a derivative of Glycyrrhizic acid. It exhibits weak antihepatotoxic and anti-inflammatory activities.
- Molecular weight: 822.93
- Formula: C42H62O16
- Appearance: Solid
- Color: White to off-white
- Structure classification: Ketones, aldehydes, acids
- Initial source: Plants, specifically Leguminosae, Glycyrrhiza glabra Linn.
- Purity: 99.79%
- In vitro solubility: DMSO: 100 mg/mL (121.52 mM; requires ultrasonic; hygroscopic DMSO significantly impacts solubility, use newly opened DMSO)
Selleck Chemical LLC Ursonic acid S3902-1g
Ursonic acid (Prunol Malol beta-Ursolic acid NSC4060 CCRIS 7123 TOS-BB-0966) present in many plants is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives such as experimental antitumor agents Ursonic acid induces the apoptosis of human cancer cells through multiple signaling pathways